Erythema nodosum - Mazginė Eritema
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2022 m. Stiftung Warentest iš Vokietijos rezultatai rodo, kad vartotojų pasitenkinimas ModelDerm buvo tik šiek tiek mažesnis nei mokamų nuotolinės medicinos konsultacijų.
2022 m. Stiftung Warentest iš Vokietijos rezultatai rodo, kad vartotojų pasitenkinimas ModelDerm buvo tik šiek tiek mažesnis nei mokamų nuotolinės medicinos konsultacijų.
Atrodo, kad tai skausmingas eriteminis mazgelis ant kojos.
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ReferencesErythema nodosum yra labiausiai paplitęs panikulito tipas, pasižymintis skausmingais raudonais mazgeliais, dažniausiai randamais ant blauzdų. Jo tiksli priežastis lieka nežinoma, tačiau manoma, kad ji atsiranda dėl per didelio organizmo atsako į įvairius veiksnius. Nors kilmė dažnai neaiški, prieš diagnozuojant pirminį erythema nodosum būtina atmesti kitas pagrindines priežastis. Tai gali būti sisteminės ligos, tokios kaip infekcijos, uždegimai, vėžys ar reakcija į vaistus. Dažniausi sukėlėjai yra strep infekcijos, tuberkuliozė, sarkoidozė, Behçet's disease, uždegiminės žarnyno ligos, tam tikri vaistai ir nėštumas.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis reiškia įvairias uždegimines ligas, turinčias įtaką riebaliniam audiniui po odos. Šios būklės vaikams yra nedažnos. Panniculitis gali būti pagrindinė sistemos problema arba antrinė reakcija į tokius veiksnius kaip infekcija, sužalojimas ar tam tikri vaistai. Nepriklausomai nuo priežasties, dauguma panniculitis tipų pasireiškia panašiais simptomais, įskaitant skausmingus, raudonus mazgelius po odos.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis, riebalinio sluoksnio po odos uždegimas, yra reta būklė, dažniausiai pasireiškianti kaip patinę mazgeliai ar dėmės. Erythema nodosum (EN) yra labiausiai paplitęs tipas, kurį dažnai sukelia įvairūs veiksniai. Nors maždaug 55 % atvejų neturi aiškios priežasties, dažniausiai sukeliančios priežastys yra infekcijos, vaistai, tam tikros ligos – pavyzdžiui, sarkoidozė ir uždegiminė žarnyno liga, nėštumas bei vėžys. EN dažniausiai pasireiškia paaugliams ir jauniems suaugusiems, ypač moterims. Prieš iškilimą dažnai jaučiamas bendras ligos pojūtis, trunkantis nuo vienos iki trijų savaičių, su simptomais, tokiais kaip karščiavimas ir viršutinių kvėpavimo takų problemos. Vėliau atsiranda raudoni mazgeliai, dažniausiai išorinėse rankų ir kojų pusėse, sukeliantys skausmą. Tiksli EN priežastis nėra visiškai aiški, tačiau manoma, kad ji susijusi su imuniniais kompleksais mažose riebalinio sluoksnio kraujagyslėse, kurie sukelia uždegimą. Paprastai biopsija parodo riebalų sluoksnio uždegimą, nepažeidžiant kraujagyslių. Net ir be aiškios pagrindinės priežasties, EN dažnai išnyksta savaime. Todėl daugumai pacientų pakanka tik simptomų palaikomosios priežiūros.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
Mazginė eritema diagnozuojama klinikiniu būdu. Norint patvirtinti neaiškią diagnozę, galima atlikti biopsiją ir ištirti ją mikroskopu. Norint atmesti plaučių ligas, ypač sarkoidozę ir tuberkuliozę, būtina atlikti krūtinės ląstos rentgenogramą.